I get random Clicks &Pops / Sample Drops over Thunderbolt on MAC OS within DAW Recording Session or Native Media Player.
Make sure your device has the latest audio drivers, which can be downloaded from the device product page.
Make sure the needed amount of buffer size is set compared to your session load.
If you get audio drop outs or session glitches
Make sure the device driversample rate is matched to your software sample rate.
-if your DAW Runs on 48.0 kHz and your Audio Midi Set-up is on 44.1 kHz this may create a internal clocking conflict.
Please make sure to always match your sample rate settings on host applications.
Turn off your WIFI when recording in your DAW.
Your computer Wifi may interfere with the Thunderbolt controller which results in clicks &pops.